Saturday's game between Leeds United and Manchester City at Elland Road might be paused in the first half to allow players observing Ramadan to break their fast.
With the match kicking off at 17:30 GMT and the sun setting in West Yorkshire at 17:41, a stoppage in play may see the likes of Omar Marmoush, Rayan Ait-Nouri, Rayan Cherki or Abdukodir Khusanov come to the side of the pitch to take on food and fluids.
Sources say a firm decision on a short break is likely to be made on Saturday morning, while it is understood Leeds would happily accommodate any such request from City.
Asked by BBC Sport if the club have to alter their schedules to help its Muslim players, manager Pep Guardiola said: "They follow this religious tradition. We have good nutritionists and they adapt to what the team needs.
"We cannot adapt the schedule for the Premier League [kick-off] times and I think they are used to it - they are not young and have been playing [for] many years during this period.
"For the players I think it is not new. Both Rayans, Omar and Khusa, it is not the first time for [observing] Ramadan and they know perfectly how to handle it."
This season, the quartet have all started together once in each of the cup competitions but are yet to feature from kick-off in the Premier League.